Best Apigenin 50mg Supplements UK 2026

By Futuro Labs Editorial Team · Published 25 May 2026

A focused comparison of 50mg apigenin supplements available in the UK — the dose backed by research and recommended in protocols like the Huberman sleep stack. Which brands deliver the cleanest formula at this dose?

At a glance

Why 50mg is the research-backed dose

The apigenin supplement market has split into two camps: brands offering 50mg per capsule and those pushing 100mg or higher. Understanding why this matters requires looking at the actual research.

Apigenin's primary mechanism for sleep support is its interaction with GABA-A receptors — the same receptor system targeted by benzodiazepines, but through a much gentler pathway. The studies examining this interaction have predominantly used doses in the 50mg range. Andrew Huberman's evening sleep protocol, which brought apigenin into mainstream supplement awareness, specifically calls for 50mg alongside magnesium L-threonate and L-theanine.

No published study has demonstrated that 100mg produces meaningfully better outcomes than 50mg. The brands offering higher doses are not citing evidence for the increase — they are using dose escalation as a marketing differentiator. For a compound that acts on GABA receptors, more is not necessarily better. Read the full 50mg vs 100mg comparison.

50mg apigenin supplements compared

SupplementPurityCapsPer DaySourceFillers
Time Health98%+ claimed120~15pGrapefruitPsyllium husk
Peak SuppsNot specified90 tabs~13pChamomileMCC, DiCaP, MgSt, SiO₂
SwansonNot specified90~15pNot specifiedNot specified
WelzoNot specified60-90~37pNot specifiedNot specified

The best 50mg options reviewed

TH Best value 50mg

Time Health Apigenin

★ 4.5/5

~£16-20 for 120 days · ~15p per day

Time Health matches the 50mg dose and claims 98%+ purity, though detailed lab results are not published. The 120-capsule count makes it the best value in the 50mg segment at roughly 15p per day. Key differences: grapefruit source (versus chamomile-derived) and psyllium husk filler.

Pros

  • 120-capsule count — best value at 50mg
  • Grapefruit-derived, 98%+ purity claimed
  • Eco-friendly recycled bottle, Ecologi tree planting

Cons

  • Lab test results not published in detail
  • Psyllium husk filler (vs brown rice flour)
  • Less manufacturing transparency than BRC AA
PS Budget 50mg

Peak Supps Apigenin

★ 4/5

~£10-14 for 90 days · ~13p per day

Peak Supps offers the cheapest 50mg option at approximately 13p per day, but uses a pressed tablet format with four additional excipients. Buyers prioritising clean labels will find this problematic. Purity is not specified on the product labelling.

Pros

  • Cheapest option in category
  • Established UK supplement brand
  • Chamomile-derived source

Cons

  • Tablet format — not capsule
  • Contains MCC, dicalcium phosphate, mag stearate, silica
  • Purity not specified

Which 50mg apigenin should you buy?

For the cleanest, most transparent 50mg apigenin available in the UK, Futuro Labs is the clear choice — 98% purity, minimal ingredients, and full lab verification. Time Health offers better value per capsule for buyers less concerned about lab test disclosure. Peak Supps suits tight budgets but comes with trade-offs in formulation purity.

Frequently asked questions

Why is 50mg the right apigenin dose?

The 50mg dose is the amount most frequently cited in sleep and longevity research protocols. Andrew Huberman's sleep stack specifically uses 50mg. Higher doses of 100mg have not demonstrated additional benefits in published studies.

Which 50mg apigenin has the fewest fillers?

Futuro Labs Apigenin contains only two ingredients: 98% apigenin and brown rice flour as a flow agent. Most other 50mg options include additional fillers, binders, or anti-caking agents.

Is 50mg apigenin enough for sleep?

For most adults, 50mg taken 30 minutes before bed is the amount supported by current research. This is the dose used in the Huberman sleep protocol and aligns with available evidence on apigenin and GABA-A receptor interaction.

Looking for a clean, lab-tested apigenin supplement?

Futuro Labs Apigenin delivers 50mg of 98% pure apigenin — BRC AA UK manufactured, zero fillers, ~22p per day.

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Last updated: 25 May 2026. All content is provided for general information only and is not intended to substitute for professional medical advice. If you have any health concerns, consult your GP or a qualified healthcare professional. Futuro Labs is a registered UK supplement manufacturer (Futuro Lab Supplements Ltd, 71-75 Shelton Street, London WC2H 9JQ). Affiliate links to Amazon UK are clearly disclosed.